New research brings us closer to understanding why that may be. Researchers from the Lewis Katz School of Medicine (LKSOM) at Temple University in Philadelphia, PA, have uncovered a mechanism that might explain why calorie restriction has such a beneficial effect on longevity.
The mechanism has to do with epigenetics and bears the name of “methylation drift.”
Scientists led by Dr. Jean-Pierre Issa, director of the Fels Institute for Cancer Research at LKSOM, explain what that means and how they have reached their conclusion in a paper published in the journal Nature Communications.
The study also suggests that the epigenetic mechanism may determine why some mammals live longer than others.